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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
14.24
Human Site:
T538
Identified Species:
31.33
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
T538
E
I
E
D
I
R
N
T
T
L
R
D
V
L
V
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
T537
E
I
E
D
I
R
N
T
T
L
R
D
V
L
V
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
T471
D
S
Q
V
L
K
A
T
A
A
L
Y
N
Q
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
T538
E
I
A
E
I
R
N
T
T
L
R
D
V
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
T538
E
I
T
D
I
R
K
T
T
L
R
D
V
L
V
Chicken
Gallus gallus
XP_425053
1523
173782
R516
E
I
R
N
T
T
F
R
D
I
L
A
A
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
G416
I
Q
R
G
R
D
F
G
L
P
S
Y
N
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
I507
E
I
A
E
L
R
K
I
T
L
W
D
I
I
V
Honey Bee
Apis mellifera
XP_624355
1492
172466
I521
E
I
A
D
I
R
R
I
T
L
W
D
V
I
V
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
I530
E
V
Q
M
I
H
S
I
T
L
R
D
I
I
K
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
V647
Q
I
D
F
I
K
K
V
K
L
W
D
I
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
100
6.6
N.A.
N.A.
N.A.
86.6
N.A.
86.6
13.3
N.A.
0
N.A.
46.6
66.6
40
33.3
P-Site Similarity:
100
100
33.3
N.A.
N.A.
N.A.
93.3
N.A.
86.6
33.3
N.A.
6.6
N.A.
73.3
73.3
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
0
0
10
0
10
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
37
0
10
0
0
10
0
0
73
0
0
10
% D
% Glu:
73
0
19
19
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
19
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
73
0
0
64
0
0
28
0
10
0
0
28
37
10
% I
% Lys:
0
0
0
0
0
19
28
0
10
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
19
0
0
0
10
73
19
0
0
37
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
28
0
0
0
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
10
19
0
0
0
0
0
0
0
0
0
0
19
0
% Q
% Arg:
0
0
19
0
10
55
10
10
0
0
46
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
10
10
0
46
64
0
0
0
0
0
10
% T
% Val:
0
10
0
10
0
0
0
10
0
0
0
0
46
10
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _